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science
Synthesis: Free Energy as the Logic of Becoming
Synthesis: Free Energy as the Master Variable
We've traveled through Gibbs free energy from formula to function—from ΔG = ΔH - TΔS to protein folding, membrane potentials, and the persistence of diamonds.
Now we step back. What does it all mean?
Free energy is not merely a thermodynamic
Membrane Potential: Gibbs Free Energy Across Barriers
Diamonds and Graphite: Thermodynamics vs Kinetics
Phase Transitions: Why Ice Melts at Exactly 0°C
Protein Folding: Finding the Free Energy Minimum
ATP Hydrolysis: The Gibbs Free Energy That Runs Your Body
Chemical Equilibrium: Where ΔG Equals Zero
human-meaning
Synthesis: What Our Fiction Says About Our Science
Synthesis: What Our Fiction Says About Our Science
We've traveled from clockwork universes to quantum branches, from Dune's attractor basins to Black Mirror's feedback traps. The journey reveals a single through-line: science fiction is the imagination processing what science means.
Not the technical details—
Black Mirror and Feedback Loops: Tech as Trap
Lem and Solaris: The Unknowable Other
Asimov's Psychohistory: Statistics as Prophecy
The MCU and Quantum Branching: Maximum Optionality
The Matrix and Wormholes: Neo Had More Choices
Dune and Attractor Basins: Paul Had to Do Jihad
biology
The CRISPR Babies: When He Jiankui Edited the Human Germline
The CRISPR Babies: When He Jiankui Edited the Human Germline
On November 25, 2018, a scientist named He Jiankui uploaded a series of videos to YouTube. He stood in what looked like a hotel conference room, speaking to the camera in careful English. He wore a blue button-down shirt. He
Base Editing and Prime Editing: Beyond Cut and Paste
CRISPR: The Gene Editing Revolution
The CRISPR Revolution
Off-Target Effects: When CRISPR Cuts in the Wrong Place
Sickle Cell Cured: The First CRISPR Miracle